The newly formed Scottish Lowland League commences playing on Saturday, August 10, with the two South clubs, Dalbeattie Star and Threave Rovers, both away from home.
The Castle Douglas side travel to play Selkirk, while Stewartry rivals Star will play Preston Athletic in Prestonpans.
Tuesday night, however, will give local fans a taste of the new league when Dalbeattie Star play hosts to neighbours Threave Rovers at Islecroft with a 7pm kick-off.
East Kilbride, who were at one time joining the South of Scotland League and are now also in the Lowland League, showed their strengths in a recent friendly against Nithsdale Wanderers when they won handsomely in a friendly match.
East Kilbride, along with Spartans and possibly Gretna 2008, look to be the teams who will test the Stewartry sides most, although most of the teams involved are of a high calibre and all will be keen to do well in the inaugural season of the new league which, in future seasons, could lead to entry into Senior football.